Link to Productivity Site

Clara Mª Pereyra López

 Graduated in Chemistry at the University of Cadiz (1991), I started my research activity in the field of Phase Equilibrium Thermodynamics, with the theoretical-experimental study of the saline effect in the distillation of aqueous mixtures, subject of my degree thesis (1992). Later, and thanks to the concession of a European project, I reorient my research work to the phase equilibrium with supercritical fluids, field in which I carried out the Doctoral Thesis (1996), after several research stays in the University of L’Aquila (Italy). After a further postdoctoral stay at the same university (2001) and with the concession of the project PPQ2003-04245 “Generation of ampicillin microparticles by the SAS technique using supercritical carbon dioxide” I was once again reorienting my research: in the field of supercritical fluids but on a more applied subject, the precipitation and encapsulation of nanoparticles. This new stage starts with the study of nanoparticle precipitation of pure compounds, and then it is implemented with the encapsulation and/or coprecipitation of the nanoparticles with biopolymers. In the last years, I have evolved towards obtaining nanoparticles from natural matrix extracts to obtain compounds with bioactive properties and their deposition in solid porous matrices. Working with polymers for encapsulation and with porous matrices for impregnation has made possible to develop the current line of research: to create our own porous matrices of biocompatible polymers by means of foaming and their impregnation with bioactive substances, always using supercritical technology. 

Link to Productivity site

Casimiro Mantell Serrano

The research activity of Casimiro Mantell has been focused on the study of extraction processes with supercritical fluids, and on the use of by-products and waste of various types of agri-food industries using different sustainable separation techniques. It has been analyzed the extraction processes using supercritical carbon dioxide, alone or with polar co-solvents, enhanced solvents extractions, pressurized liquid solvents, and extraction with subcritical water. All this activity has been realized in the research group named “Analysis and Design of Processes with Supercritical Fluids”, directed by Dr. Enrique Martínez de la Ossa, from 1995.
He has been the responsible of three research projects financed by the Spanish government, call in 2012, 2015 and 2020, and he has participated in numerous projects of this call at the research team. He has also been responsible of a project of the state agency for international cooperation with Morocco (PCI projects) and has participated in two more with Bolivia. On the other hand, he has directed several research contracts with companies (CEPSA, BIOOILS, Olivar de Segura, Los Bresnos Agricola, Phytoplant Research …) with a total financing amounting of € 234,000. In addition, he is co-author of three patents related to the valorization of agri-food by-products and he is working on the creation of a SpinOff in order to take advantage of the knowledge that has been developed in recent years in the research group related to extraction with Supercritical Fluid